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The LNG-IUS remains in place in the uterus and releases the progestin levonorgestrel for up to 5 years, therefore being considered as a good long-term options.

After the LNG-IUS is inserted, there may be heaver periods initially. However, periods become short eventually with little to no blood acetazolamide. For many women, the LNG-IUS completely stops menstrual periods. Common side effects may include cramping, acne, back pain, breast tenderness, headache, mood changes, and nausea.

The LNG-IUS may increase the risk for pen v cysts, but such cysts Polidocanol Injection (Asclera)- FDA cause no symptoms and resolve on their Privigen (Immune Globulin Intravenous)- FDA Women who have a pen v of pelvic inflammatory disease or who have had a serious pelvic infection pen v not use the LNG-IUS.

Depo-Provera (also called Depo or DMPA) uses the progestin medroxyprogesterone acetate, which is administered by injection once every 3 months.

Most women who use Depo-Provera stop menstruating altogether after a year. Pen v may be beneficial for women with heavy bleeding, or pain due pen v endometriosis. Women who eventually want to have children should be aware that Depo-Provera can cause persistent infertility for up to 22 months after the last injection, although the average is 10 months. Weight gain can be a problem, particularly in women who are already overweight.

Women should not use Depo-Provera if they have a history of liver disease, blood clots, stroke, or cancer of the reproductive organs. Depo-Provera should not be used for longer than 2 years because it can cause loss of bone density. Gonadotropin releasing hormone pen v agonists are sometimes used to treat severe menorrhagia.

GnRH agonists block the release of the reproductive hormones LH (luteinizing hormone) and FSH (follicular-stimulating hormone). As a result, the pen v stop ovulating and no longer produce estrogen. GnRH agonists include the implant goserelin (Zoladex), a monthly injection pen v leuprolide (Lupron Depot), and the nasal spray nafarelin (Synarel).

Several new oral GnRH antagonists (elagolix and relugolix) are available. They have similar action of the ovaries as the GnRH agonists. Such drugs may be used alone or in preparation for procedures used to destroy the uterine lining.

They are not pen v suitable for long-term use. Commonly reported side effects, which can be severe in some women, include menopausal-like symptoms. These symptoms include hot flashes, night sweats, changes in the vagina, weight change, and depression. The side effects vary in intensity depending on the GnRH agonist. They may pen v more intense with leuprolide and persist after the pen v has been stopped. The most important concern is possible osteoporosis from estrogen loss.

Women should not take these drugs for more than 6 months. Add-back therapy, which provides doses of estrogen and progestin that are high enough to maintain bone density but are too low to offset the beneficial effects of the GnRH agonist, may be used.

GnRH pen v may increase the risk for birth defects. Women who are taking GnRH agonists should use non-hormonal birth control methods, such pen v the diaphragm, cervical cap, or condoms. Pen v (Danocrine) is a synthetic substance that resembles a male hormone.

It suppresses estrogen, and therefore menstruation, and is occasionally used (sometimes in combination with an oral contraceptive) to ginseng extract panax prevent heavy bleeding. It is not suitable for long-term use, and due to its masculinizing side effects it is only used in rare cases. GnRH agonists have largely replaced the use of danazol. Adverse side effects include facial hair, deepening of the voice, weight gain, acne, pen v reduced breast size.

Danazol may also increase the risk for unhealthy cholesterol levels and it may cause birth defects. Tranexamic acid (Lysteda) is a newer medication for treating heavy menstrual bleeding and the first non-hormonal drug for menorrhagia treatment.

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