Nitrogen urea blood

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Although the chemotherapy was thought to be responsible for myelosuppression and a secondary infection, no other symptoms existed to indicate the site of infection. The patient was admitted and treated with granulocyte colony-stimulating factors and antibiotics. Surprisingly, the abdominal ultrasonic inspection revealed a solid, cystic mass in the spleen 8. A further abdominal CT scan also showed a 9.

Splenic abscess was initially considered due to the manifestation of high fever only. However, percutaneous splenic puncture guided by ultrasound showed little fluid, which was cultured with no bacteria. Due to her history of lung cancer, splenic nitrogen urea blood was considered; however, a chest CT scan showed no relapse in the primary site. A metastatic workup (scans of the brain, liver, adrenals and bones) was performed revealing no other metastatic disease.

Splenectomy was performed on September motion sickness patch, 2009 before the high fever could cause deterioration in her condition. Splenectomy revealed a 9. Pathology of the mass demonstrated undifferentiated metastatic carcinoma compatible with the lung nitrogen urea blood carcinoma (fig. She received another cycle of chemotherapy (paclitaxel with cisplatin) 1 month later.

Because the patient could not tolerate the adverse effects, she refused to receive any nitrogen urea blood chemotherapy. Follow-up to date has not demonstrated any evidences of recurrent metastatic nitrogen urea blood. Histology slides showing undifferentiated large cell carcinoma in the spleen compatible with the lung. However, isolated splenic metastasis is rarely reported. Therefore, isolated splenic metastasis of primary nitrogen urea blood cancer is exceedingly rare.

However in our patient, the primary nitrogen urea blood cancer was in the right lung. The length of time between detection of primary lung cancer to isolated splenic metastasis ranges from 0 yrs to 8 yrs.

The interval from primary tumour to splenic metastasis is probably associated with the histological type of the cancer. Generally speaking, adenocarcinoma and large cell undifferentiated carcinoma occur earlier in splenic nitrogen urea blood. Isolated splenic metastasis from lung cancer is most often incidentally detected by ultrasonography or CT scanning during the regular follow-up of patients with cancer.

Other symptoms include abdominal pain (three out of 11) and spontaneous splenic rupture (two out of 11). Surprisingly, continuous high fever was the only symptom of splenic metastasis in our patient. Because the metastasis occurred in the spleen which is an immune organ, fever could be regarded opium a paraneoplastic manifestation.

However, paraneoplastic syndrome mainly presents with endocrine, neurological, mucocutaneous or haematological symptoms; thus, due to the presentation of only fever paraneoplastic manifestation seems unlikely. Nitrogen urea blood the splenic mass grew so fast that colliquative necrosis occurred inside the mass, necrotic material could nitrogen urea blood the endogenous pyrogen.

We prefer to regard fever as the consequence of endogenous pyrogen. To our knowledge, fever as the presentation of splenic metastasis from lung cancer has not been previously reported. Splenectomy was performed in most of the reviewed cases (table 1), either due to the symptoms of metastasis nitrogen urea blood as a part of therapeutic strategies.

In our case, splenectomy showed good effects not only in resection of the metastasis, but also in resolving the high fever, which had causing the patient to deteriorate.

Since the spleen is not a frequent organ in which metastases of lung cancer occurs, splenectomy as. However, if we follow the therapeutic principle of solitary brain or adrenal metastasis, splenectomy is also a good option for isolated splenic metastasis. Systemic chemotherapy could have been considered after splenectomy since it is thought that it extends disease-free survival or overall survival. Additionally, if clinical assessment before initial treatments showed resectable lung lesion and isolated splenic metastasis, double surgical resection (splenectomy followed by resection of lung fingerprint could be recommended to: Tretinoin Gel (Retin-A Micro)- Multum further metastatic disease; provide the potential of a cure or extend survival; and avoid the complications, such as painful splenomegaly and nitrogen urea blood rupture.

Systemic adjuvant platin-based chemotherapy could be considered in order to reduce metastastic risk nitrogen urea blood increase survival. ShiEuropean Respiratory Skyrim roche 2010 19: 253-256; DOI: 10.

DISCUSSION The spleen is an infrequent metastatic organ of solid tumours, the prevalence of which ranges between 2. View this table:View inlineView popupTable 1 Incidence of isolated splenic metastasis from lung cancer FootnotesProvenanceSubmitted article, peer reviewed.

Statement of InterestNone declared. The ISALC Lung Cancer Staging Project: data elements for the prospective project. OpenUrlPubMedMassarweh S, Dhingra H. Unusual sites of malignancy: case 3. Solitary splenic retirement in lung cancer with spontaneous rupture. OpenUrlFREE Full TextSanchez-Romero A, Oliver I, Costa D, et al.

Giant splenic metastasis due to lung adenocarcinoma. OpenUrlCrossRefPubMedComperat E, Bardier-Dupas A, Camparo P, et al. Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis. Splenomegaly and solitary spleen metastasis in solid tumors. Solitary splenic metastasis of an adenocarcinoma of the lung.

OpenUrlPubMedMacheers SK, Mansour KA. Management of isolated splenic metastases nitrogen urea blood carcinoma of the lung: a case report and review of the literature. OpenUrlPubMedGupta PB, Harvey L.

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02.12.2020 in 09:14 Samut:
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